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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">kaz29</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник Казахстанско-Британского технического университета</journal-title><trans-title-group xml:lang="en"><trans-title>Herald of the Kazakh-British Technical University</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-6688</issn><issn pub-type="epub">2959-8109</issn><publisher><publisher-name>Казахстанско-Британский Технический Университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.55452/1998-6688-2026-23-3-328-335</article-id><article-id custom-type="elpub" pub-id-type="custom">kaz29-3195</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МАТЕМАТИЧЕСКИЕ НАУКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MATHEMATICAL SCIENCES</subject></subj-group></article-categories><title-group><article-title>МОДИФИЦИРОВАННАЯ SEIR МОДЕЛЬ С GRID AUTO-SEARCH ОПТИМИЗАЦИЕЙ ДЛЯ ВЫСОКОТОЧНОГО ПРОГНОЗИРОВАНИЯ ДИНАМИКИ ЭПИДЕМИЙ НА ОСНОВЕ COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>MODIFIED SEIR MODEL WITH GRID AUTO-SEARCH OPTIMIZATION FOR HIGH-ACCURACY EPIDEMIC DYNAMICS FORECASTING BASED ON COVID-19</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2143-3994</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куатбаева</surname><given-names>A. A.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuatbaeva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>PhD, ассистент-профессор</p><p>Астана</p></bio><bio xml:lang="en"><p>PhD, Assistant Professor</p><p>Astana</p></bio><email xlink:type="simple">a.kuatbayeva@astanait.edu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-8883-7073</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Омарбеков</surname><given-names>A. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Omarbekov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Магистр</p><p>Астана</p></bio><bio xml:lang="en"><p>MSc.</p><p>Astana</p></bio><email xlink:type="simple">242929@astanait.edu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-6188-8021</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аян</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aian</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Магистр</p><p>Астана</p></bio><bio xml:lang="en"><p>MSc.</p><p>Astana</p></bio><email xlink:type="simple">241785@astanait.edu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Astana IT university</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>Astana IT university</institution><country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>26</day><month>09</month><year>2026</year></pub-date><volume>23</volume><issue>3</issue><fpage>328</fpage><lpage>335</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Куатбаева A.A., Омарбеков A.Н., Аян А.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Куатбаева A.A., Омарбеков A.Н., Аян А.А.</copyright-holder><copyright-holder xml:lang="en">Kuatbaeva A.A., Omarbekov A.N., Aian A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.kbtu.edu.kz/jour/article/view/3195">https://vestnik.kbtu.edu.kz/jour/article/view/3195</self-uri><abstract><p>В статье представлена модифицированная эпидемиологическая модель SEIR, интегрированная с методами машинного обучения для повышения точности прогнозирования динамики распространения COVID-19. Модель SEIR, более сложная, добавляет категорию «контактных» пациентов, которые способны передавать инфекцию, но еще не проявили симптомы. Такая модель позволяет лучше понять динамику эпидемий, особенно с длительным инкубационным периодом, который усложняет выявление заболевания и увеличивает риск его распространения. Предложенный подход расширяет классическую модель за счет временно-зависимых параметров, отражающих влияние мер социальной изоляции, уровня вакцинации и мобильности населения. Методология Grid Auto-Search обеспечивает автоматическую оптимизацию параметров и адаптивный выбор периода обучения. Для прогнозирования временно-зависимого коэффициента передачи β(t) применялись алгоритмы XGBoost и LSTM. Датасет включает 1143 наблюдения по Франции из трех открытых источников (Johns Hopkins University, Our World in Data, Google Mobility). Разработанная модель демонстрирует R² до 0,96 на горизонтах 30–90 дней; кросс-валидация подтверждает отсутствие существенного переобучения. Полученные результаты обосновывают практическую применимость гибридного подхода для систем поддержки принятия решений в здравоохранении. Результаты исследования подтверждены двумя авторскими свидетельствами Qazpatent на объекты авторского права.</p></abstract><trans-abstract xml:lang="en"><p>This paper presents a modified SEIR epidemiological model integrated with machine learning techniques to improve COVID-19 transmission dynamics forecasting. The proposed approach extends the classical framework with time-dependent parameters capturing the effects of social distancing, vaccination coverage, and population mobility. The Grid Auto-Search methodology enables automatic parameter optimization and adaptive trainingperiod selection. XGBoost and LSTM algorithms are applied to forecast the time-varying transmission coefficient β(t). The dataset comprises 1,143 daily observations for France from three open sources (Johns Hopkins University, Our World in Data, Google Mobility). The model achieves R² up to 0.96 across 30–90-day horizons; crossvalidation confirms the absence of significant overfitting. The results support the practical applicability of this hybrid approach for healthcare decision-support systems. The research results are confirmed by two Qazpatent certificates of copyright registration.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>SEIR модель</kwd><kwd>COVID-19</kwd><kwd>эпидемиологическое прогнозирование</kwd><kwd>Grid Auto-Search</kwd><kwd>параметрическая оптимизация</kwd><kwd>XGBoost</kwd><kwd>LSTM</kwd><kwd>временные ряды</kwd><kwd>математическое моделирование</kwd><kwd>мобильность населения</kwd><kwd>вакцинация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>SEIR model</kwd><kwd>COVID-19</kwd><kwd>epidemiological forecasting</kwd><kwd>Grid Auto-Search</kwd><kwd>parameter optimization</kwd><kwd>XGBoost</kwd><kwd>LSTM</kwd><kwd>time series</kwd><kwd>mathematical modeling</kwd><kwd>population mobility</kwd><kwd>vaccination</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Our World in Data. COVID-19 Data Repository (2024). 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